Researchers seek to improve the identification of patients with Parkinson’s disease who would benefit from neurostimulation.
BOSTON—Full-scale IQ and list learning are the best predictors of cognitive change following bilateral subthalamic nucleus deep brain stimulation (DBS), investigators reported at the 2012 Annual Meeting of the American Neurological Association. Preoperative full-scale IQ may account for 53% of postoperative variance in cognition. Full-scale IQ and list learning combined may account for 67% of postoperative cognitive variance.
Delayed story recall, single-word retrieval, and verbal fluency had significant positive correlations with cognitive change but did not contribute significantly to variance, said Angela Costello, D ClinPsych. Executive function had a significant negative correlation with postoperative cognitive change.