SSRIs and SNRIs may have a beneficial effect on mood and seizure frequency in patients with epilepsy.
SAN DIEGO—Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants did not increase seizure frequency in a retrospective series of epilepsy patients, as reported at the 64th Annual Meeting of the American Epilepsy Society.
The researchers investigated how 84 adult patients with epilepsy fared after taking the drugs for six months. None of the patients had an increase—and some actually had a decrease—in seizure frequency, and almost all had improvements in their baseline depression and anxiety.
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