Individuals older than 70 with nonmelanoma skin cancer may have a significantly reduced risk of developing Alzheimer’s disease, compared with individuals without nonmelanoma skin cancer, according to research published online ahead of print... More

Depression in late life can accelerate cognitive decline. A new study shows that depression in older adults significantly increased the risk of all-cause dementia, Alzheimer’s disease, and vascular dementia.

Depression... More

The age-adjusted death rate for Alzheimer’s disease in Washington State was more than four times higher than the rate in Hawaii for 2010, according to a report from the Centers for Disease Control and Prevention.

Washington had a... More

Self-reported rates of confusion or memory loss and of related functional difficulties in adults aged 60 years and older varied considerably by race/ethnicity, according to a report from the Centers for Disease Control and... More

ORLANDO—Treatment of patients with multiple sclerosis (MS) with human multipotent adult progenitor cells may provide clinical benefit through modulation of immune status and promotion of remyelination, according to basic... More

ORLANDO—Exercise training is associated with a significant moderate reduction in fatigue among patients with multiple sclerosis (MS), according to data presented at the Fifth Cooperative Meeting of the Consortium of... More

ORLANDO—In natalizumab-treated patients with multiple sclerosis (MS) and no prior immunosuppressant use, a higher anti-JCV antibody index correlates with an increased risk of progressive multifocal leukoencephalopathy... More

STOWE, VERMONT—Advance planning for rescue therapy can prevent the need for a patient with headache to visit the emergency room, Rebecca Burch, MD, stated at the 23rd Annual Winter Headache Symposium of the Headache... More

HONOLULU—What if you could scan your patients for stroke-susceptibility loci or implant a device in their brains to repair stroke-damaged pathways?

Such forward-thinking concepts may be achievable,... More

SAN DIEGO—Of the items in the most current Alzheimer’s disease diagnostic criteria, PET imaging with 18-fluorodeoxyglucose is the strongest individual positive predictive biomarker of short-term incident dementia in mild... More

The word pain originates from the Latin word poena, meaning punishment, an accurate descriptor of how chronic pain affects the daily lives of millions of afflicted individuals. A 2011 Institute of Medicine report, Relieving Pain in... More

In a large series of adult and pediatric patients with juvenile-onset, unexplained, chronic widespread pain, more than half met rigorous, multi-test diagnostic criteria for small-fiber polyneuropathy (SFPN), according to a report in the... More

SAN DIEGO—Fingolimod slows brain atrophy in patients with multiple sclerosis (MS) and is the only approved drug that does so within the first six months of treatment, reported Jeffrey Cohen, MD, at the 65th Annual Meeting... More

The publication of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) on May 27 marks the first time that the influential diagnostic manual has been updated in nearly 20 years. The goal... More

SAN DIEGO—Among older retired players from the National Football League (NFL) who have a history of concussion, about 40% have mild to moderate symptoms of depression, a rate nearly three times higher than that of the... More

To prevent migraine attacks, neurologists commonly prescribe drugs designed to treat epilepsy, high blood pressure, or depression. Monoclonal antibodies currently in development could one day become the first prophylactic therapies... More

SAN DIEGO—Post-traumatic stress disorder (PTSD) preceded a diagnosis of psychogenic nonepileptic seizures in 58% of military veterans and a diagnosis of epileptic seizures in 14% of military veterans, according to Martin... More

HONOLULU—Patients admitted to the hospital with ischemic stroke who undergo embolectomy may still have a substantially increased risk of subsequent ischemic stroke. In research presented at the 2013 International Stroke... More

There is a known risk of stroke whenever surgery or intravascular treatments are performed on brain-supplying blood vessels. That risk involves complications immediately or soon after the intervention, as well as a subsequent risk of... More

BETHESDA, MARYLAND—Surgery cures half of patients with refractory temporal lobe epilepsy, yet it is still highly underused, in part because of misperceptions about the risks and benefits, according to Edward F. Chang,... More

SAN DIEGO—Resective surgery is a successful treatment for many patients with intractable epilepsy, but the risk factors for seizure recurrence have been unclear. A study presented at the 65th Annual Meeting of the American... More

SAN DIEGO—Simvastatin may reduce the rate of brain atrophy by approximately 40% in patients with secondary progressive multiple sclerosis (SPMS), according to data presented at the 65th Annual Meeting of the American... More

HONOLULU—Attention and visuospatial ability three months after stroke may be strong predictors of patients’ long-term quality of life. Mental processing speed in the acute stage, particularly choice reaction time, also may... More

SAN DIEGO—Epidemiologic studies of neurologic conditions have inconsistent methodologies that result in differing estimates of disease prevalence, according to research presented at the 65th Annual Meeting of the American... More

STOWE, VERMONT—Headache therapies of the near future will include new delivery routes for established medications, as well as comparatively new nerve-stimulation techniques, according to an overview presented at the 23rd... More

SAN DIEGO—Diffusion tensor imaging (DTI) may help neurologists detect axonal injury before any symptoms appear in an athlete who has had a concussion, said Jeffrey J. Bazarian, MD, MPH. Neurologists can maximize the... More

Preclinical beta-amyloid deposition in the brains of cognitively normal volunteers was associated with poor sleep quality, but not sleep quantity, according to a study published in the May issue of JAMA Neurology.

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SAN DIEGO—Despite arguments to the contrary, amyloid imaging can have clinical benefits for patients with suspected dementia, according to research presented at the 65th Annual Meeting of the American Academy of Neurology.... More