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vol. 10 no. 12
December 2002
December 2002 Issue

Cover Article
Does Drinking Wine Help Keep Dementia Away?
Recent research has found that individuals who drink wine on a weekly or monthly basis are 60% to 70% less likely to develop later dementia than are non-wine drinkers. For daily wine drinkers, however, no protective effect was seen. So, just what exactly is the relationship between wine consumption and risk of dementia?

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vol. 10 no. 11
November 2002
November 2002 Issue

Cover Article
Late Recovery After Major Spinal Cord Injury—Is It Possible?
The Christopher Reeve “N of One” Study

The story of Christopher Reeve’s struggle to recover after a major spinal cord injury is remarkable not because of the celebrity status of the patient but because he has achieved what most considered impossible: partial recovery of sensory and motor function seven years after his injury.

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vol. 10 no. 10
October 2002
October 2002 Issue

Cover Article
A Sounder Mind in a Healthier Body?
Recent epidemiologic evidence suggests that a range of lifestyle elements, including diet and nutrition, cholesterol level, body weight, exercise, blood pressure, intellectual stimulation, and social interaction may have a role in preventing or delaying the onset of Alzheimer’s disease.

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vol. 10 no. 9
September 2002
September 2002 Issue

Cover Article
A Window of Opportunity Opens When Alzheimer’s Disease Is Detected in Its Earliest Stages
Mild cognitive impairment is so subtle that it can be, and often is, mistaken for normal aging. But since mild cognitive impairment very often progresses to Alzheimer’s disease, clinicians who detect it may effectively be catching Alzheimer’s disease at a very early stage, when interventions may be most effective and patients can participate in treatment and planning for the future.

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vol. 10 no. 8
August 2002
August 2002 Issue

Cover Article
Unraveling the Mystery of the MS Lesion—Pathogenic Clues and Therapeutic Hints
A large pathology sample of patients with MS revealed “profound heterogeneity in the immunopathologic appearance of active MS lesions,” reported Claudia Lucchinetti, MD. At the 54th Annual Meeting of the American Academy of Neurology, Dr. Lucchinetti identified the four patterns she and her research team observed and discussed the implications such findings may have on future MS research.

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vol. 10 no. 7
July 2002
July 2002 Issue

Cover Article
The Mind’s Eye—Neuroscience, Synesthesia, and Art
Experimental evidence suggests that synesthesia results from cross wiring between known anatomical regions in the brain. These findings are used as a springboard to propose a new synthetic bootstrapping theory of the origin and evolution of language and the significance of artistic expression.

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vol. 10 no. 6
June 2002
June 2002 Issue

Cover Article
Alzheimer’s Disease Risk—Who Wants to Know, and Why?
Since genetic testing for Alzheimer’s disease offers no definitive answers as to whether an individual may or may not get the neurodegenerative disease, and since there is no cure, who would want to undergo genotyping? Two related studies presented at the 54th Annual Meeting of the American Academy of Neurology looked at the number and motivation of children of patients with Alzheimer’s disease who were willing to undergo genetic susceptibility testing.

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vol. 10 no. 5
May 2002
May 2002 Issue

Cover Article
Driving With Dementia—What Is the Physician’s Role?
Determining whether a driver is unsafe, addressing and treating the patient with dementia, and telling a patient that he or she should no longer drive are challenging issues confronting physicians. At the 15th Annual Meeting of the American Association for Geriatric Psychiatry, Dr. William Roccaforte offered some suggestions for dealing with these challenging issues.

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vol. 10 no. 4
April 2002
April 2002 Issue

Cover Article
Tighter Control of Blood Pressure Can Prevent More Strokes
"Most strokes occur not in people with severe hypertension but in those with mild hypertension, with systolic readings between 140 and 159," reported Philip Wolf, MD, at the 27th International Stroke Conference. The problem is, many of these people don't know they are at risk and are not being treated.

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vol. 10 no. 3
March 2002
March 2002 Issue

Cover Article
Women Taking AEDs May Need Calcium Boost
Nearly three quarters of premenopausal women with epilepsy taking an antiepileptic (AED) have a calcium intake association between long-term AED treatment and bone disease. Women with epilepsy should be regularly monitored to ensure that they are getting enough calcium, advised Hyunmi Choi, MD, and colleagues.

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vol. 10 no. 2
February 2002
February 2002 Issue

Cover Article
An Underestimated Cause of Epilepsy Misdiagnosis
It is well accepted among epileptologists that more damage is done by overreading than by underreading EEGs. Nevertheless, epileptologists frequently encounter EEGs that have been overread, resulting in erroneous diagnoses of epilepsy. "But the interesting thing here is neurologists who don't read EEGs all the time, rather than erring on the side of underreading, err on the side of overreading," reported Selim Benbadis at the 2001 Annual Meeting of the American Epilepsy Society.

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Vol. 10, No. 1
January 2002
January 2002 Issue

Cover Article
Significant Benefits From Cholesterol-Lowering Therapy, Regardless of Baseline Cholesterol Level
Results of the largest cholesterol-lowering study to date have shown that a broad range of patients, regardless of their baseline or posttreatment cholesterol level‚ will benefit from treatment with a cholesterol–lowering drug. Reporting at the American Heart Association’s 2001 Scientific Sessions‚ reaserchers estimated that cholesterol lowering with statin treament reduces the risk of heart attack and stroke by nearly one third.

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