Are Effective Therapies for Progressive MS on the Horizon?
INDIANAPOLIS—Although many drugs have failed in clinical trials to provide benefits to patients with progressive... More
Can Brain MRIs Diagnose and Classify Migraine?
WASHINGTON, DC—Accurate classifiers for the diagnosis and subclassification of migraine have been developed using brain... More
Identification by Protein Redirects Clinical Diagnosis of Neurodegenerative Diseases
WASHINGTON, DC—Years of investigation into cellular mechanisms has produced a translational shift in the approach to... More
How Do Stroke and Sleep Apnea Affect Cognition?
WASHINGTON, DC—Patients with stroke and sleep apnea may have worse memory and executive function, compared with... More
Allan Krumholz, MD
Dr. Krumholz, lead author of the AAN/AES guideline on management of first unprovoked seizures, discusses the key points... More

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—Self-reported monitoring through an automated telehealth mechanism can provide a valid assessment of disease-modifying therapy (DMT) adherence among patients with multiple sclerosis (MS), according to study findings reported at the 201... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—Although many women with multiple sclerosis (MS) are perimenopausal, the literature contains few data about effective ways to manage these women’s symptoms, according to research presented at the 2015 CMSC Annual Meeting. The topic c... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—Smoked cannabis may compromise cognitive function in patients with multiple sclerosis (MS), according to an overview presented at the 2015 Consortium of MS Centers Annual Meeting. Evidence does not support the hypothesis that cannabis ... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—A standardized MRI is important for the diagnosis and follow-up of patients with multiple sclerosis (MS). However, acquisition and interpretation of MRI scans may be complicated due to differences in pulse sequence (eg, FLAIR vs PD/T2)... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—For patients with multiple sclerosis (MS), making treatment decisions is a complex undertaking. The decisions involve clinical factors such as symptom severity, level of disability, and disease duration. Physician recommendations play ... More »
 
Emergency medical services (EMS) use for stroke differs by race, ethnicity, and sex, according to a study published in the August issue of the Journal of the American Heart Association. Data were analyzed from 398,798 stroke patients who were admitte... More »
 

American Academy of Neurology

WASHINGTON, DC—Clinical studies have yet to show that nondopaminergic drugs improve motor disability in Parkinson’s disease to the same degree that dopaminergic drugs do. Nondopaminergic agents may reduce motor complications, however, if administ... More »
 

American Headache Society

WASHINGTON, DC—While migraine is debilitating on an individual and societal level, its effects on the entire family can be substantial, as well. In a survey of migraineurs and their spouse/partners, migraine was found to impact family activities, i... More »
 
For the first time, progressive multifocal leukoencephalopathy (PML) has been reported in patients with multiple sclerosis (MS) treated with fingolimod who had not previously been treated with an immunosuppressant, according to an FDA warning issued ... More »
 

Alzheimer's Association International Conference

WASHINGTON, DC—A randomized, double-blind, placebo-controlled trial found that a commercially available dietary supplement may improve recent verbal memory. The supplement, Alpha BRAIN, includes Huperzia serrata, an herb that contains huperzine A,... More »
 
Successful treatment with antihypertensive medications does not reduce the risk of stroke to the level of a person who is normotensive without medication, according to research published in the June issue of Stroke. Furthermore, stroke risk increases... More »
 

Associated Professional Sleep Societies

SEATTLE—Sleep disturbances are associated with worse cognitive performance, particularly within the domain of executive function, according to data presented at the 29th Annual Meeting of the Associated Professional Sleep Societies. The results sug... More »
 
Among current smokers, migraine may increase the risk of stroke and combined vascular events, according to research published online ahead of print July 22 in Neurology. Migraine may not be associated with these outcomes among nonsmokers, however. T... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—Investigators are conducting clinical trials of various drugs that may slow clinical worsening in patients with progressive multiple sclerosis (MS), according to an overview provided at the 2015 CMSC Annual Meeting. Two such agents, an... More »
 

Alzheimer's Association International Conference

WASHINGTON, DC—RVT-101, an oral 5-HT6 receptor antagonist, provided statistically significant improvements in cognition and function to patients with mild-to-moderate Alzheimer’s disease who were receiving donepezil, compared with patients receiv... More »
 

American Headache Society

WASHINGTON, DC—Every neurologist who treats headache sees patients who are overusing medication. At the 57th Annual Meeting of the American Headache Society, Stewart J. Tepper, MD, discussed the recognition and diagnosis of medication overuse heada... More »
 
Peripheral plasma levels of the CNS protein tau are chronically elevated after traumatic brain injury (TBI) and appear to correlate with the severity of postconcussive symptoms, according to a report published online ahead of print August 3 in JAMA N... More »
 

Associated Professional Sleep Societies

SEATTLE—Increased restless legs syndrome (RLS) severity is associated with increased risk of stroke, according to a study described at the 29th Annual Meeting of the Associated Professional Sleep Societies. The association between RLS severity and ... More »
 

Alzheimer's Association International Conference

WASHINGTON, DC—Patients in late life with type 1 diabetes have an approximately 93% increased risk of dementia, compared with patients who do not have diabetes, according to data from a 12-year observational study described at the 2015 Alzheimer’... More »
 

Alzheimer's Association International Conference

WASHINGTON, DC—Women with mild cognitive impairment (MCI) decline faster on measures of cognition and function than men over a period of up to eight years, according to an analysis presented at the 2015 Alzheimer’s Association International Confe... More »
 

International Headache Congress

VALENCIA, SPAIN—Following a schedule of regular daily mealtimes, bedtimes, and aerobic exercise is an effective yet underused approach for the management of migraine, said Yohannes W. Woldeamanuel, MD, at the 17th Congress of the International Head... More »
 
An elevated rate of autism traits was seen among a cohort of children exposed to antiepileptic drugs (AEDs) in utero. Study findings were reported in the July Epilepsia. “The most important determinant of association with autistic traits was higher... More »
 
TORONTO—The brains of people with epilepsy appear to react to music differently from the brains of those who do not have the disorder, according to research presented at the American Psychological Association’s 123rd Annual Convention. Researcher... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—The community of organisms housed in the intestines—the gut microbiome—may differ significantly between patients with multiple sclerosis (MS) and healthy controls, preliminary study results show. “The most exciting possibility i... More »
 

Associated Professional Sleep Societies

SEATTLE—A habitual sleep duration of seven hours is associated with peak cognitive performance for all age groups except the elderly, according to data presented at the 29th Annual Meeting of the Associated Professional Sleep Societies. Sleep durat... More »
 

American Headache Society

WASHINGTON, DC—Noncephalic pain is associated with a higher likelihood of progression from episodic migraine to chronic migraine, according to research presented at the 57th Annual Scientific Meeting of the American Headache Society. The findings ... More »
 

Alzheimer's Association International Conference

At the 2015 Alzheimer's Association International Conference, Drs. Friedhoff and Lombardo discuss results from the completer analysis of RVT-101 as an adjunct to donepezil in adults with mild to moderate Alzheimer’s disease.... More »
 

Alzheimer's Association International Conference

Dr. Whitmer discusses the first study of dementia risk in patients with Type 1 diabetes.... More »
 

Vanderbilt Symposium

At the recent Vanderbilt Symposium in Hilton Head, South Carolina, Dr. Abou-Khalil describes laser ablation as a treatment for epilepsy.... More »
 

Vanderbilt Symposium

Dr. Kirshner reviews emerging treatments for Alzheimer's disease at the Vanderbilt Symposium.... More »
 

International Congress of Parkinson’s Disease and Movement Disorders

At the 19th International Congress of Parkinson's Disease and Movement Disorders, Dr. LeWitt describes new levodopa preparations in development.... More »
 
Dr. Thadani discusses the range of neuromodulation strategies available for the treatment of seizures, proper patient selection, and treatment outcomes. ... More »
 
An open-label study indicates that patients with multiple sclerosis may benefit from switching to alemtuzumab.... More »
 
Dr. Ardeshna discusses the unique challenges posed by epilepsy in the rapidly expanding elderly population. ... More »
 
Does amyloid accumulation cause the cognitive decline observed in middle age?... More »
 
An investigator on the ESCAPE trial examines the current evidence for endovascular therapy in acute ischemic stroke.... More »
 

JULY 2015

This supplement highlights the on-site reporting prepared by the editorial staff of Neurology Reviews.... More »
 

MARCH 2015

This supplement is sponsored by Raptor Pharmaceuticals Inc.... More »