Identification by Protein Redirects Clinical Diagnosis of Neurodegenerative Diseases
WASHINGTON, DC—Years of investigation into cellular mechanisms has produced a translational shift in the approach to... More
How Do Stroke and Sleep Apnea Affect Cognition?
WASHINGTON, DC—Patients with stroke and sleep apnea may have worse memory and executive function, compared with... More
Allan Krumholz, MD
Dr. Krumholz, lead author of the AAN/AES guideline on management of first unprovoked seizures, discusses the key points... More
Does Amyloid Accumulation Cause Midlife Cognitive Decline?
Cognitive decline in middle age may not result from β-amyloid deposition, according to a study published online ahead... More
Stroke Survivors May Have Increased Risk of Cancer
NASHVILLE—The annual rate of age-adjusted cancer incidence is higher among patients who have had ischemic stroke,... More

International Congress of Parkinson’s Disease and Movement Disorders

SAN DIEGO—Patients with early Parkinson’s disease who started treatment with a rotigotine transdermal patch six months earlier than other patients had a slower return to baseline mean Unified Parkinson’s Disease Rating Scale (UPDRS) II and III ... More »
 

International Congress of Parkinson’s Disease and Movement Disorders

SAN DIEGO—Initiating regular exercise outside of structured interventions is associated with a slower decline in quality of life in patients with Parkinson’s disease, according to research presented at the 19th International Congress of Parkinson... More »
 

International Congress of Parkinson’s Disease and Movement Disorders

SAN DIEGO—Inhaled levodopa rapidly improves motor function when patients with Parkinson’s disease use the therapy at the onset of off states, according to research presented at the 19th International Congress of Parkinson’s Disease and Movement... More »
 

International Congress of Parkinson’s Disease and Movement Disorders

SAN DIEGO—Dopamine transporter (DAT) scans may identify prodromal Parkinson’s disease in patients with REM sleep behavior disorder (RBD), according to research presented at the 19th International Congress of Parkinson’s Disease and Movement Dis... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—Self-reported monitoring through an automated telehealth mechanism can provide a valid assessment of disease-modifying therapy (DMT) adherence among patients with multiple sclerosis (MS), according to study findings reported at the 201... More »
 
Cognitive behavioral therapy for insomnia (CBT-I) is an effective treatment for adults with chronic insomnia, according to a review published online ahead of print June 9 in Annals of Internal Medicine. Researchers analyzed 20 randomized controlled t... More »
 

American Academy of Neurology

WASHINGTON, DC—Measuring transcutaneous carbon dioxide partial pressure (TCpCO2) may identify increased seizure severity and duration, according to research described at the 67th Annual Meeting of the American Academy of Neurology. The technique al... More »
 

American Academy of Neurology

WASHINGTON, DC—Nonmotor symptoms of Parkinson’s disease, including problems with vision, cognition, mood, and sleep, may be targeted with various behavioral and environmental interventions, according to a presentation at the 67th Annual Meeting o... More »
 
Two decades ago, the NINDS study showed that IV t-PA was relatively effective when treating physicians used only a CT scan and a checklist dominated by time and comorbidities to choose recipients of IV t-PA. Later studies showed that the decision to ... More »
 
Brain imaging signs may not indicate an increased risk of symptomatic intracranial hemorrhage after treatment with IV t-PA, according to a study in the May Lancet Neurology. Certain early ischemic and pre-existing signs are associated with reduced in... More »
 
Low muscle strength in late adolescence may indicate the presence of subclinical motor deficits and predict a subsequent diagnosis of Parkinson’s disease, according to data published May 5 in Neurology. “The pattern of reduced muscle strength onl... More »
 

International Headache Congress

VALENCIA, SPAIN—Medication overuse headache (MOH) is strongly associated with high stress levels and several unhealthy but modifiable behaviors, according to a large Danish population-based study. “High stress plus smoking, low physical activity... More »
 

American Academy of Neurology

WASHINGTON, DC—Investigators are examining alpha-synuclein as a target for Parkinson’s disease therapy in various ways, according to a presentation at the at the 67th Annual Meeting of the American Academy of Neurology. “You can block rele... More »
 

American Academy of Neurology

WASHINGTON, DC—A novel threshold tracking transcranial magnetic stimulation (TMS) technique reliably distinguishes between amyotrophic lateral sclerosis (ALS) and non-ALS disorders, according to research presented at the 67th Annual Meeting of the ... More »
 

American Academy of Neurology

WASHINGTON, DC—A new investigational drug for Rett syndrome is well tolerated and may provide clinical benefit, according to a presentation at the 67th Annual Meeting of the American Academy of Neurology. Currently, no therapy is approved for the t... More »
 

American Academy of Neurology

WASHINGTON, DC—The Four-Variable Screening Tool may be a useful method of screening for obstructive sleep apnea within 90 days of stroke, according to study results presented at the 67th Annual Meeting of the American Academy of Neurology. The vari... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—Compared with interferon β-1a, daclizumab high-yield process (DAC HYP) may provide greater improvement in the patient-centered outcomes of ambulation and cognition for patients with relapsing-remitting multiple sclerosis (MS), accordi... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—Most patients with relapsing-remitting multiple sclerosis (MS) remain free of new MRI activity for four years after initiating treatment with alemtuzumab, according to data presented at the 2015 CMSC Annual Meeting. Alemtuzumab also ap... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—A majority of patients remain stable when switching from natalizumab to dimethyl fumarate, according to data presented at the 2015 CMSC Annual Meeting. Factors such as sex, age, and duration of natalizumab treatment may predict the pro... More »
 

Consortium of Multiple Sclerosis Centers

INDIANAPOLIS—Early detection of progressive multifocal leukoencephalopathy (PML) may improve outcomes, according to an update presented at the 2015 CMSC Annual Meeting. When PML results from reversible immunosuppression, as in patients with multipl... More »
 

American Academy of Neurology

WASHINGTON, DC—Familial genetic studies suggest that GLUT1 deficiency may be more common among patients with epilepsy than previously understood, according to Ingrid Scheffer, MBBS, PhD, Professor of Pediatric Neurology at the University of Melbour... More »
 

American Academy of Neurology

WASHINGTON, DC—Among patients with Parkinson’s disease, aerobic exercise may improve white matter integrity in the putamen, according to research presented at the 67th Annual Meeting of the American Academy of Neurology. The increased white matte... More »
 

American Academy of Neurology

WASHINGTON, DC—The motor subtype classification of patients with Parkinson’s disease may shift over time, according to research presented at the 67th Annual Meeting of the American Academy of Neurology. Patients primarily shift from a tremor-domi... More »
 

American Academy of Neurology

WASHINGTON, DC—A drug that contains dextromethorphan and quinidine may reduce agitation in patients with Alzheimer’s disease, according to a study described at the 67th Annual Meeting of the American Academy of Neurology. The drug, known as AVP-9... More »
 

American Academy of Neurology

WASHINGTON, DC—Patients taking perampanel may not require routine laboratory monitoring, according to data from three trials presented at the 67th Annual Meeting of the American Academy of Neurology. Those taking the adjunctive seizure treatment sh... More »
 
The concept that biotin, a water-soluble vitamin, could have a beneficial effect on the course of multiple sclerosis (MS) is biologically plausible. Biotin activates acetyl-CoA carboxylase, a potential rate-limiting enzyme in myelin synthesis, and ha... More »
 

American Headache Society

Dr. Buse discusses an analysis of actual dialogues between general neurologists and patients with chronic migraine during routine office visits and offers suggestions for improving physician–patient communication.... More »
 

American Headache Society

At the 57th Annual Meeting of the American Headache Society, Dr. Bond discusses clinical pain catastrophizing in women with migraine and obesity.... More »
 

American Headache Society

Dr. Bigal discusses the findings from two phase IIb clinical trials of TEV-48125, a CGRP monoclonal antibody, for the preventive treatment of chronic migraine and for high-frequency episodic migraine.... More »
 

Associated Professional Sleep Societies

Dr. Gao provides data at SLEEP 2015 suggesting that RLS is associated with subsequent stroke.... More »
 

Associated Professional Sleep Societies

At SLEEP 2015, Dr. Ramos described a link between sleep disturbances and decline in executive function.... More »
 
Dr. Thadani discusses the range of neuromodulation strategies available for the treatment of seizures, proper patient selection, and treatment outcomes. ... More »
 
An open-label study indicates that patients with multiple sclerosis may benefit from switching to alemtuzumab.... More »
 
Dr. Ardeshna discusses the unique challenges posed by epilepsy in the rapidly expanding elderly population. ... More »
 
Does amyloid accumulation cause the cognitive decline observed in middle age?... More »
 
An investigator on the ESCAPE trial examines the current evidence for endovascular therapy in acute ischemic stroke.... More »
 

MARCH 2015

This supplement is sponsored by Raptor Pharmaceuticals Inc.... More »
 

MARCH 2015

This advertorial is sponsored by Cadwell Laboratories, Inc.... More »